Journal of Fluorine Chemistry p. 143 - 150 (1986)
Update date:2022-08-05
Topics:
Kitazume, Tomoya
Murata, Kouichi
Ikeya, Takanobu
A synthetic approach to optically pure (+)-2-fluoromalonic acid monoethyl ester was based on the enantiotopic specificity of asymmetric hydrolysis by an immobilized enzyme. The absolute configuration of monoethyl (+)-2-fluoromalonate was determined : it is the (R)-enantiomer.
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