Bioorganic and Medicinal Chemistry Letters p. 219 - 224 (1997)
Update date:2022-08-05
Topics:
Beeley
Berge
Chapman
Dean
Kelly
Lowden
Kotecha
Morgan
Rami
Thompson
Vong
Ward
A simplified template approach was used to delineate the structural requirements for high potency and intrinsic activity of aryloxypropanolamines as agonists at the human beta-3 adrenoceptor. The information generated was used to prepare selective beta-3 adrenoceptor agonists.
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