Journal of the Chemical Society. Perkin transactions I p. 706 - 711 (1981)
Update date:2022-09-26
Topics:
Brockwell, Michael A.
Caldwell, A. Gordon
Whittaker, Norman
Begley, Michael J.
The enantiomers of the two diastereomers of 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin have been synthesised.Potent inhibition of platelet aggregation in this series is associated with the configuration corresponding to that in the natural inhibitors, such as prostaglandins E1 and D2.
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