2-Benzazepines. 1. Synthesis of 2-Benzazepin-4-ones and -5-ones via 2-Acetylenic Benzophenones

DOI: 10.1021/jo00133a040

Source and publish data:

Journal of Organic Chemistry p. 2441 - 2447 (1982)

Update date:2022-09-26

Topics:

Authors:

Trybulski, Eugene J.

Reeder, Earl

Blount, John F.

Walser, Armin

Fryer, R. Ian

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Article abstract of DOI:10.1021/jo00133a040

The preparation of 1-phenyl-2-benzazepin-4-ones and -5-ones is discussed.The palladium-catalyzed coupling of an iodobenzophenone to a monosubstituted acetylene assembles the necessary atoms required for the benzazepine ring.Transformation of the acetylene

Full text of DOI:10.1021/jo00133a040

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