Studies on Terpenes. 8. Total Synthesis of (+/-)-Linderalactone, (+/-)-Isolinderalactone, and (+/-)-Neolinderalactone, Germacrane Furanosesquiterpenes

Article abstract of DOI:10.1021/jo00187a004

The synthesis of linderalactone (1), isolinderalactone (2), and neolinderalactone (3) is described and exploits the unique ability of these fluxional systems to enter into Cope and abnormal Cope rearrangements.The symmetrical β-diketone 10 was converted i