Journal of Medicinal Chemistry p. 688 - 690 (1980)
Update date:2022-08-04
Topics:
Rogers, M. E.
Wilkinson, D. S.
Thweatt, J. R.
Halenda, S. P.
A series of spiro analogues of the potent narcotic ketobemidone have been prepared and found to be devoid of opiate activity.Additional pharmacology and possible implications for the mode of binding of ketobemidone to the analgesic receptor are discussed.
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