Inhibitors of indoleethylamine N-methyltransferase. Derivatives of 3-methyl-2-thiazolidinimine. In vitro, in vivo, and metabolic studies

DOI: 10.1021/jm00181a014

Source and publish data:

Journal of Medicinal Chemistry p. 773 - 780 (1980)

Update date:2022-08-05

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Authors:

Rokach Rokach

Girard Girard

Hamel Hamel

Reader Reader

Rooney Rooney

Mandel Mandel

Cragoe Jr.

Zacchei Zacchei

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Article abstract of DOI:10.1021/jm00181a014

A variety of substituent groups has been attached to the exocyclic imine function of 2-imino-3-methylthiazolidine in a search for metabolic precursors of this potent inhibitor of the enzyme indoleethylamine N-methyltransferase (INMT) which would exhibit s

Full text of DOI:10.1021/jm00181a014

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