Inhibitors of indoleethylamine N-methyltransferase. Derivatives of 3-methyl-2-thiazolidinimine. In vitro, in vivo, and metabolic studies

Article abstract of DOI:10.1021/jm00181a014

A variety of substituent groups has been attached to the exocyclic imine function of 2-imino-3-methylthiazolidine in a search for metabolic precursors of this potent inhibitor of the enzyme indoleethylamine N-methyltransferase (INMT) which would exhibit s