Helvetica Chimica Acta p. 250 - 254 (1980)
Update date:2022-08-04
Topics:
Keller-Schierlein, Walter
Joos, Beda
D,L-4-Oxo-homotyrosine was synthesized by the acetylaminomalonic ester pathway.The optical resolution was carried out by means of the enzyme acylase I.The L-configuration of the enzymatically produced amino acid was confirmed by degradation to L-aspartic acid. 4-Oxo-homotyrosine obtained by degradation of the polypeptide antibiotic echinocandine B has D-configuration, but his optical purity is low.A hypothetical explanation for its formation from the (2S,3S,4S)-3,4-dihydroxyhomotyrosine residue of echinocandine B is proposed.
View MoreContact:+86-21-61318535
Address:Building 29,No.2139 Xizha Road, Fengxian District, Shanghai
Jiangxi Province Bethel Pharmaceutical Co., Ltd.
Contact:+86-795-259 3456 ，+86-15957688008 13566650571
Address:Huangjindui Chemical Park， Shanggao County ，Yichun city，Jiangxi Province
Penglai Qianwei Chemical Co., Ltd.
Contact:86-535-3357802
Address:Shahelu (north), Penglai, Shandong, China
Shanghai Massive Chemical Technology Co., Ltd.
website:http://www.massivechem.com/
Contact:+86 21 34943721
Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Chengda Pharmaceuticals Co., Ltd.
Contact:+86-573-84601188
Address:hengshan Road 5# in Jiashan, zhejiang
Doi:10.1016/j.tet.2004.11.020
(2005)Doi:10.1002/chem.201605836
(2017)Doi:10.1021/acs.jmedchem.8b00389
(2018)Doi:10.1016/S0957-4166(02)00542-6
(2002)Doi:10.1021/jo9004348
(2009)Doi:10.1021/jo4018099
(2013)
