
Bioorganic and Medicinal Chemistry Letters (2020)
Update date:2022-09-26
Topics:
Wang, Xiaofang
Cal, Monica
Kaiser, Marcel
Buckner, Frederick S.
Lepesheva, Galina I.
Sanford, Austin G.
Wallick, Alexander I.
Davis, Paul H.
Vennerstrom, Jonathan L.
Pyridyl benzamide 2 is a potent inhibitor of Trypanosoma cruzi, but not other protozoan parasites, and had a selectivity-index of ≥10. The initial structure–activity relationship (SAR) indicates that benzamide and sulfonamide functional groups, and N-meth
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