An expeditious synthesis of dimethyl 1-benzyl-cis-piperidine-3,5-dicarboxylate

Article abstract of DOI:10.1080/00397919708004806

A mixture of dimethyl 1-benzyl-cis- and trans-piperidine-3,5-dicarboxylate is prepared in high yields from readily available starting materials, by a reliable procedure. The straightforward conversion of the mixture into the diastereomerically pure cis-isomer, a useful σ-symmetry intermediate for alkaloid synthesis, is also prescribed.

Full text of DOI:10.1080/00397919708004806

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An Expeditious Synthesis
of Dimethyl 1-Benzyl-cis-
Piperidine-3,5-Dicarboxylate
Bruno Danieli a , Giordano Lesma a , Daniele
Passarella a & Alessandra Silvani a
a Dipartimento di Chimica Organica e
Industriale , Università degli Studi di Milano-
Centro CNR di Studio sulle Sostanze Organiche
Naturali , Via Venezian 21, 20133, Milano, Italy
Published online: 19 Aug 2006.
To cite this article: Bruno Danieli , Giordano Lesma , Daniele Passarella &
Alessandra Silvani (1997) An Expeditious Synthesis of Dimethyl 1-Benzyl-cis-
Piperidine-3,5-Dicarboxylate, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 27:1, 69-77, DOI:
10.1080/00397919708004806
To link to this article: http://dx.doi.org/10.1080/00397919708004806
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