N,N'-diisopropyl-O-diphenylmethyl isourea: A mild and convenient alklating agent for the formation of cephalosporin derivatives derivatives

Article abstract of DOI:10.1080/00397919808007035

N,N'-Diisopropyl-O-diphenylmethyl isourea reacts with cephalosporin-4- carboxylic acid in tetrahydrofuran at room temperature to give the diphenylmethyl (DPM) ester in good yields without isomerization of the double bond from C-3 to C-2.

Full text of DOI:10.1080/00397919808007035

Synthetic Communications
ISSN: 0039-7911 (Print) 1532-2432 (Online) Journal homepage: http://www.tandfonline.com/loi/lsyc20
N,N'-Diisopropyl-O-Diphenylmethyl Isourea: A
Mild and Convenient Alkylating Agent for the
Formation of Cephalosporin Derivatives
Kyung Hoi Cha , Tae Won Kang , Hong-Woo Lee , Eung-Nam Kim , Nam-Hee
Choi , Jung-Woo Kim & Chung-Il Hong
To cite this article: Kyung Hoi Cha , Tae Won Kang , Hong-Woo Lee , Eung-Nam Kim , Nam-
Hee Choi , Jung-Woo Kim & Chung-Il Hong (1998) N,N'-Diisopropyl-O-Diphenylmethyl Isourea:
A Mild and Convenient Alkylating Agent for the Formation of Cephalosporin Derivatives,
Synthetic Communications, 28:12, 2207-2211, DOI: 10.1080/00397919808007035
To link to this article: http://dx.doi.org/10.1080/00397919808007035
Published online: 02 Sep 2006.
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Date: 01 March 2016, At: 06:14