Synthesis of 2'- and 3'-acetoxyolivetols [5-(2- and 3-acetoxypentyl)-1,3-benzenediols]: Key intermediates in the synthesis of tetrahydrocannabinol derivatives

Article abstract of DOI:10.1055/s-1980-29193

Generally, the synthesis of side-chain derivatives of THC's has been achieved by condensation of the appropriately substituted olivetol with a monoterpene, e.g., the biologically potent metabolite 3'-hydroxy-Δ¹-THC was synthesized from 3'-aceto