Introduction of Sulfur Containing Substituents into 6-Amino-4-methylsalicylates

Article abstract of DOI:10.1002/ardp.19803130903

The reaction of the azasulfonium salt 2, formed by the addition of N-chlorosuccinimide to dimethyl sulfide, with methyl 4-methyl-6-(propylamino)salicylate (1) affords the sulfonium betaine 4, With nitric acid 4 is converted into <2-hydroxy-3-methoxycarbon