2-Benzazepines. 6. Synthesis and Pharmacological Properties of the Metabolites of 9-Chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine

DOI: 10.1021/jm00365a009

Source and publish data:

Journal of Medicinal Chemistry p. 1596 - 1601 (1983)

Update date:2022-09-26

Topics:

Authors:

Trybulski, Eugene J.

Fryer, R. Ian

Reeder, Earl

Walser, Armin

Blount, John

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00365a009

The 2-benzazepine 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepine (1) has been selected for development as an anxiolytic agent.In support of this program, we have confirmed by chemical synthesis the structures of three in vitro (rat liver hom

Full text of DOI:10.1021/jm00365a009

Products guided by the article

Product name:9-chloro-7-(2-chlorophenyl)-6,7-dihydro-6-<(4-methylphenyl)sulfonyl>-5H-pyrimido<5,4-d><2>benzazepine

Cas No:76988-74-4

R&D Labs maybe for 76988-74-4

Jinan Great Chemical Co.,Ltd.

Contact:+86-531-58668191 58668193 58668196 58661173

Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
Jinan Baozhao Pharmaceutical Co., Ltd

Contact:0086-531-86397156 82371858 82371868

Address:Huaneng Road, Jinan, Shandong ,China
Daqing E-shine Chemical Co.,LTD

Contact:0086-024-31285112

Address:Hongweiyuan area, Ranghulu district
Zibo Jujin Chemical Industry Co., Ltd.（Dongming Jujin Chemical Industry Co., Ltd. ）

Contact:+86-533-2975022

Address:No.99 Shanquan Road, Zhangdian District
Ji'an Hairui Natural Plant Co. Ltd.

Contact:0796-8105528

Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province

Relevant to this article

CHIRAL PHENYLPHOSPHONIC ESTERS, THEIR PREPARATION VIA ETHYL N- L-PROLINATE AND THEIR ABSOLUTE CONFIGURATIONS

Doi:10.1246/cl.1980.1403
(1980)
Optically Active Selenoxides: Chromatographic Separation and Absolute Configuration

Doi:10.1021/jo00391a043
(1987)
Synthesis of 2-amino-5-arylthiazoles by palladium-catalyzed arylation at the C5 position with aryl iodides

Doi:10.1055/s-2007-992368
(2007)
Doi:10.1021/ja00400a084
(1981)
Studies on the syntheses of heterocyclic and natural compounds. 950. Asymmetric total synthesis of (+)-chenodeoxycholic acid. Stereoselectivity of intramolecular cycloaddition of olefinic o-quinodimethanes

Doi:10.1021/jo00133a020
(1982)
ELECTRON-TRANSFER PROCESSES. NEW SYNTHESIS OF γ-LACTONES BY PEROXYDISULFATE OXIDATION OF ISOPROPYLBENZENES AND ALIPHATIC CARBOXYLIC ACIDS

Doi:10.1016/0040-4020(80)88052-5
(1980)

Article Doi