2-Benzazepines. 6. Synthesis and Pharmacological Properties of the Metabolites of 9-Chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine

DOI: 10.1021/jm00365a009

Source and publish data:

Journal of Medicinal Chemistry p. 1596 - 1601 (1983)

Update date:2022-09-26

Topics:

Authors:

Trybulski, Eugene J.

Fryer, R. Ian

Reeder, Earl

Walser, Armin

Blount, John

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00365a009

The 2-benzazepine 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepine (1) has been selected for development as an anxiolytic agent.In support of this program, we have confirmed by chemical synthesis the structures of three in vitro (rat liver hom

Full text of DOI:10.1021/jm00365a009

Products guided by the article

Product name:9-chloro-7-(2-chlorophenyl)-6,7-dihydro-6-<(4-methylphenyl)sulfonyl>-5H-pyrimido<5,4-d><2>benzazepine

Cas No:76988-74-4

R&D Labs maybe for 76988-74-4

ShiJiaZhuang Dowell Chemical Co.,Ltd.

website:http://www.dowechem.com

Contact:+86-13463963265

Address:Xiyangling village, high tech Zone, Shijiazhuang，Hebei, China
EGBERT CORPORATION

Contact:+86 18616952870

Address:Area
Hubei ShiNan Pharmaceutical Chemical co., Ltd.(expird)

Contact:+86-13554447107

Address:Wuhan HongShanOu wu no road 378 future residence building 1 unit 14 layer no. 1401 A
Hefei EnliPharma Tecnology Co.,Ltd

Contact:0086-551-66399836

Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china

Relevant to this article

CHIRAL PHENYLPHOSPHONIC ESTERS, THEIR PREPARATION VIA ETHYL N- L-PROLINATE AND THEIR ABSOLUTE CONFIGURATIONS

Doi:10.1246/cl.1980.1403
(1980)
Optically Active Selenoxides: Chromatographic Separation and Absolute Configuration

Doi:10.1021/jo00391a043
(1987)
Synthesis of 2-amino-5-arylthiazoles by palladium-catalyzed arylation at the C5 position with aryl iodides

Doi:10.1055/s-2007-992368
(2007)
Doi:10.1021/ja00400a084
(1981)
Studies on the syntheses of heterocyclic and natural compounds. 950. Asymmetric total synthesis of (+)-chenodeoxycholic acid. Stereoselectivity of intramolecular cycloaddition of olefinic o-quinodimethanes

Doi:10.1021/jo00133a020
(1982)
ELECTRON-TRANSFER PROCESSES. NEW SYNTHESIS OF γ-LACTONES BY PEROXYDISULFATE OXIDATION OF ISOPROPYLBENZENES AND ALIPHATIC CARBOXYLIC ACIDS

Doi:10.1016/0040-4020(80)88052-5
(1980)

Article Doi