2-Benzazepines. 6. Synthesis and Pharmacological Properties of the Metabolites of 9-Chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine

DOI: 10.1021/jm00365a009

Source and publish data:

Journal of Medicinal Chemistry p. 1596 - 1601 (1983)

Update date:2022-09-26

Topics:

Authors:

Trybulski, Eugene J.

Fryer, R. Ian

Reeder, Earl

Walser, Armin

Blount, John

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Article abstract of DOI:10.1021/jm00365a009

The 2-benzazepine 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepine (1) has been selected for development as an anxiolytic agent.In support of this program, we have confirmed by chemical synthesis the structures of three in vitro (rat liver hom

Full text of DOI:10.1021/jm00365a009

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Product name:9-chloro-7-(2-chlorophenyl)-6,7-dihydro-6-<(4-methylphenyl)sulfonyl>-5H-pyrimido<5,4-d><2>benzazepine

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