Journal of Organic Chemistry p. 1469 - 1474 (1981)
Update date:2022-08-04
Topics:
Miller, Roger W.
Powell, Richard G.
Smith, Cecil R.
A new antileukemic taxane alkaloid, cephalomannine (1a), has been isolated from leaves, stems, and roots of Taxus wallichiana Zucc.Cephalomannine is closely related to taxol (1b), a previously characterized antileukemic alkaloid, which also occurs in T. wallichiana but in lesser amounts than cephalomannine.The new alkaloid and its hydrolysis products were characterized by nuclear magnetic resonance, mass spetroscopy, and X-ray crystallography; taxol and two cytotoxic taxane congeners were also identified.
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Doi:10.1016/j.bmcl.2007.07.020
(2007)Doi:10.1246/bcsj.39.1253
(1966)Doi:10.1021/ja00391a066
(1981)Doi:10.1016/S0040-4039(00)78757-0
(1980)Doi:10.1039/b409714a
(2004)Doi:10.1021/ja00547a051
(1980)
