2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

Article abstract of DOI:10.1021/jm00365a008

A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepine-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different