2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

DOI: 10.1021/jm00365a008

Source and publish data:

Journal of Medicinal Chemistry p. 1589 - 1596 (1983)

Update date:2022-08-05

Topics:

Authors:

Trybulski, Eugene J.

Benjamin, Louis E.

Earley, James V.

Fryer, R. Ian

Gilman, Norman W.

et al. et al.

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Article abstract of DOI:10.1021/jm00365a008

A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepine-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different

Full text of DOI:10.1021/jm00365a008

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