
Tetrahedron Letters p. 2925 - 2928 (1992)
Update date:2022-08-03
Topics:
Beeson, Craig
Pham, Nguyen
Dix, Thomas A.
The stereochemistry of β-hydroxyesters produced in the NaBH4 reduction of alicyclic β-ketoesters has been determined.An enhanced rate of reduction has been observed for those isomers in which the carboxylate is antiperiplanar to the hydride ion in the tra
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