Journal of the Chemical Society. Chemical communications p. 1224 - 1226 (1980)
Update date:2022-08-04
Topics: Synthesis Acylation Regioselectivity Heterocyclic compounds Deprotonation Organic synthesis Coumarin Carboxylic Acids Benzofuran Chromone VINYL CARBANIONS Flavone Anionic Intermediate Synthetic Methodology
Costa, Ana M. B. S. R. C. S.
Dean, Francis M.
Jones, Michael A.
Smith, Dennis A.
Varma, Rajender S.
Lithium di-isopropylamide at -70 deg C can remove the α-proton from benzofuran in the absence of activating groups and the β-proton if such groups are present; in flavone and 4-methoxycoumarin β-deprotonation occurs readily and the carbanions are easily carboxylated giving acids not previously accessible, while in 2,6-dimethylchromone β-deprotonation is kinetically favoured allowing 3-acylation to be achieved separately from the conventional acylation at the 2-methyl group.
View MoreShaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Xi'an yuanfar international trade company
website:https://www.yuanfarchemical.com
Contact:86-029-88745613 ext 828
Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
Shanxi Tongji Pharmaceuticals Co., Ltd.
Contact:+86-359-3024784
Address:Xikuang South Road, Ruicheng County , Shanxi
Nantong Auxin Electronic Technology Co., LTD
Contact:86-513-88760026
Address:NO.5-1, Aoxin Road, Haian Hi-tech Development Zone, Jiangsu Province, China
Hangzhou jls Flame Retardants Chemical Co.,Ltd
Contact:+86-571-87250387/87250386
Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
Doi:10.1016/j.jssc.2008.02.021
(2008)Doi:10.1039/c39800001182
(1980)Doi:10.1021/ja992059f
(2000)Doi:10.1021/jo01106a624
(1958)Doi:10.1016/0040-4020(80)80151-7
(1980)Doi:10.1002/chem.200400144
(2004)
