Journal of the Chemical Society. Chemical communications p. 424 - 425 (1981)
Update date:2022-08-04
Topics:
Morris, David S.
Williams, Dudley H.
Norris, Alan F.
The four possible stereoisomers of a new metabolite of vitamin D3, 25-hydroxycholecalciferol-26,23-lactone, have been synthesized; we establish that the natural product has the 23R,25S stereochemistry, and that it has < 1percent of the activity of vitamin D3 in bringing about intestinal calcium absorption.
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Doi:10.1002/adsc.201800774
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