Some 7-Substituted 4-(Trifluoromethyl)coumarins

Article abstract of DOI:10.1021/je00025a041

Preparation and spectral properties are given for 13 substituted 4-(trifluoromethyl)coumarins (7-hydroxy, 7,8-dihydroxy, 6-ethyl-7-hydroxy, 6-benzyl-7-hydroxy, 7-methoxy, 7-methyl, 7-amino, 7-(ethylamino), 7-(benzylamino), 7-anilino, 7-<(trifluoroethyl)amino>, 7-<(pentadecafluorooctyl)amino>, and 2(1H)-isoindolyl).Three 7-(acylamido)-4-(trifluoromethyl)coumarins (acetyl, benzoyl, and bromoacetyl) were also prepared as well as two new phenol precursors, 3-<(pentadecafluorooctyl)amino>phenol and 2-(3-hydroxyphenyl)-1H-isoindole.