Chemistry Letters p. 675 - 678 (1981)
Update date:2022-07-30
Topics:
Kasai, Hiroshi
Shiomi, Tomoko
Sugimura, Takashi
Nishimura, Susumi
A potent mutagen, 2-amino-3,8-dimethylimidazo<4,5-f>quinoxaline (Me-IQx), isolated from fried beef and its 3,7-dimethyl derivative were synthesized from 6-amino-3-methylquinoxaline and 6-amino-2-methylquinoxaline, respectively.These compounds showed strong mutagenic activity towards Salmonella typhimurium TA98 in the presence of S9 Mix.
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Doi:10.1016/S0040-4039(03)00245-4
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(2020)
