
Journal of the Chemical Society. Perkin transactions I p. 1729 - 1733 (1981)
Update date:2022-08-05
Topics:
Roberts, Stanley M.
Woolley, Geoffrey T.
Newton, Roger F.
The lactone (4) reacted with the cuprate reagents (5) and (6) under standard conditions to give mainly the products (8) and (12) respectively derived from an SN' anti-process.Under the same conditions the lactone (15) reacted with the cuprate reagents (5) and (6) through the SN2 mode primarily to give as the major products the acids (23) and (19) respectively.The compounds (15), (19), and (23) were converted into the corresponding prostaglandin A2 analogues (18), (22), and (26).
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Doi:10.1021/jo00138a028
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(1981)Doi:10.1021/jm00142a018
(1981)Doi:10.1016/S0040-4039(01)82919-1
(1981)Doi:10.1021/jo00336a025
(1981)