A GENERAL ROUTE TOWARD 2-OXO-, 2-THIOXO- AND 2-IMINOPENAMS AND THEIR CONVERSION INTO 2-ALKOXY-, 2-ALKYLTHIO- AND 2-AMINOPENEMS

DOI: 10.1016/S0040-4039(00)81982-6

Source and publish data:

Tetrahedron Letters p. 2563 - 2566 (1983)

Update date:2022-08-03

Topics:

Authors:

Cossement, Marc

Marchand-Brynaert, Jacqueline

Bogdan, Sophie

Ghosez, Leon

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Article abstract of DOI:10.1016/S0040-4039(00)81982-6

A convenient methodology is described which allows the preparation of 2-oxo-, 2-thioxo- and 2-iminopenams from a single precursor readily prepared from penicillin G.These penams have been converted into the corresponding 2-heterosubstituted penems.

Full text of DOI:10.1016/S0040-4039(00)81982-6

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