
Tetrahedron Letters p. 2563 - 2566 (1983)
Update date:2022-08-03
Topics:
Cossement, Marc
Marchand-Brynaert, Jacqueline
Bogdan, Sophie
Ghosez, Leon
A convenient methodology is described which allows the preparation of 2-oxo-, 2-thioxo- and 2-iminopenams from a single precursor readily prepared from penicillin G.These penams have been converted into the corresponding 2-heterosubstituted penems.
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