Evaluation of sparteine-like chiral diamines in the enantioselective lithiation-electrophilic trapping of an O-alkyl carbamate

Article abstract of DOI:10.1039/b600032k

Seven (+)-sparteine-like diamines and (-)-sparteine were evaluated in the diamine-mediated asymmetric lithiation-trapping of an O-alkyl carbamate. The (+)-sparteine-like diamines (≥98: 2 er by chiral shift NMR spectroscopy) were prepared from (-)-cytisine