Journal of Medicinal Chemistry p. 405 - 412 (1980)
Update date:2022-07-31
Topics:
Boehme, E. H. W.
Bambury, R. E.
Baumann, R. J.
Erickson, R. C.
Harrison, B. L.
et al.
A number of orally active cephalosporins and penicillins with interesting biological activity were synthesized.Two of these, 7-<<<3,4-(methylenedioxy)phenyl>glycyl>amino>deacetoxycephalosporanic acid and 7-<<2-(2,3-dihydro-5-benzofuranyl)glycyl>amino>deacetoxycephalosporanic acid were considerably more active than cephalexin both in vitro and in vivo against staphylococcal and streptococcal infections.
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