Long-Bridged Cyclonucleosides. 1. Synthesis and Reactions of Some Purine 8,2'-(Nα-Methylhydrazino) and 8,2'-(Nα-Methyloxamido) Cyclonucleosides

DOI: 10.1021/jo00338a023

Source and publish data:

Journal of Organic Chemistry p. 5176 - 5181 (1981)

Update date:2022-08-05

Topics:

Authors:

Sasaki, Tadashi

Minamoto, Katsumaro

Yamashita, Shunsuke

Yamaguchi, Katsuhiko

Miyake, Kuniko

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Article abstract of DOI:10.1021/jo00338a023

For expansion of the range of the model conformations of cyclonucleosides, synthesis of some long-bridged purine cyclonucleosides has been achieved.Thus, 8-bromo-2'-O-tosyladenosine (1a) and its guanine analogue (1b) with methylhydrazine gave the correspo

Full text of DOI:10.1021/jo00338a023

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