Journal of the American Chemical Society p. 7615 - 7620 (1981)
Update date:2022-07-29
Topics:
Stewart, Walter W.
3,6-Disulfonated 4-aminonaphthalimides are stable, highly fluorescent, water-soluble compounds. A general synthesis of these compounds is presented: a primary amine is condensed in aqueous acid with 4-amino-3,6-disulfonaphthalic anhydride, and the product is isolated as its crystalline potassium, sodium, or lithium salt. The anhydride, whose preparation is described in detail, is interesting because it is stable indefinitely in boiling water and crystallizes readily when the solution is cooled. Because of their intense yellow-green fluorescence, solubility in water, and ability to be bound to cells and tissues, two of these 4-aminonaphthalimides have proved useful as biological tracers, and their synthesis is described in detail.
View MoreContact:86-511-85210668 0511-85210668, 85210818, 85210898
Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
Suzhou Time-chem Technologies Co., Ltd.
Contact:0512-63983931/68086856
Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
Refine Chemicals Science & Technology Technology Developing Co., Ltd.
Contact:+86-22-87899130
Address:No.12,west keyan road,Tianjin City
Nanjing Norris Pharm Technology Co., Ltd.
Contact:+86-13901585132
Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
Cangzhou Senary Chemical Science-tech Co., Ltd
Contact:+86-317-3563899, 3563699
Address:168 Jinde Road, Cangzhou, Hebei, China
Doi:10.1021/jm00345a018
(1982)Doi:10.1007/BF00568517
(1981)Doi:10.1002/adsc.202001021
(2020)Doi:10.1021/jo00344a008
(1982)Doi:10.1016/S0022-328X(00)98509-7
(1983)Doi:10.1021/ja00369a034
(1982)