New Synthesis of 2-Substituted 2-Oxazolines: Transition-Metal-Catalyzed Cross-Coupling of Grignards with 2-(Methylthio)-4,4-dimethyl-2-oxazoline

DOI: 10.1021/jo00339a032

Source and publish data:

Journal of Organic Chemistry p. 5402 - 5404 (1981)

Update date:2022-08-04

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Authors:

Pridgen, Lendon N.

Killmer, Lewis B.

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Article abstract of DOI:10.1021/jo00339a032

A new synthesis of 2-aryl-4,4-dimethyl-2-oxazolines (18a-e) using nickel- and palladium-phosphine complexes to catalyze cross-coupling of Grignard reagents 17 with 2-(methylthio)-4,4-dimethyl-2-oxazoline (16) is described.This reaction represents the firs

Full text of DOI:10.1021/jo00339a032

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