Tetrahedron Letters p. 5899 - 5902 (1984)
Update date:2022-08-03
Topics:
Bessodes, M.
Abushanab, E.
Antonakis, K
The title compounds were prepared enantiospecifically by kinetic resolution of (+/-) 1-nonene-3-ol via Sharpless oxidation.The products 1,2R-epoxy-nonane-3S-ol and 1-nonene-3R-ol were efficiently converted to all four stereoisomers of 2-hydroxy-3-nonylamine, which were subsequently incorporated into the target hypoxanthines to evaluate their immunopotentiating activity.
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