Synthesis of (E)-1-(5-Chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-Dichlorophenylhydrazone Hydrochloride, a Novel, Orally Active Antifungal Agent

DOI: 10.1021/jm00357a023

Source and publish data:

Journal of Medicinal Chemistry p. 442 - 445 (1983)

Update date:2022-08-03

Topics:

Authors:

Dyer, R.L.

Ellames, G.J.

Hamill, B.J.

Manley, P.W.

Pope, A.M.S.

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Article abstract of DOI:10.1021/jm00357a023

The preparation, determination of isomeric configuration, and antifungal properties of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride (1) are described.In vitro, compound 1 has been shown to have activity

Full text of DOI:10.1021/jm00357a023

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