Tetrahedron p. 3061 - 3066 (1981)
Update date:2022-09-26
Topics: Synthesis Heterocyclic compounds Side-chain Oxidative degradation
Lugosi, Peter
Schawartz, Jozsef
Doleschall, Gabor
A novel method for the oxidative degradation of the side-chain of 3-(3-haloisoxazol-5-yl) propionic acids has been developed.The E-3-(3-chloroisoxazol-5-yl) propenoic acid 13a obtained by treatment of the s-triazolo<2,3-c> quinazolin-4-ium iodide 11a with PhI(OAc)2 and Bz2O2, respectively, and subsequent hydroxysis, has been used for the synthesis of numerous 3-haloisoxazole derivatives.
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Doi:10.1039/P19810003265
(1981)Doi:10.1016/0031-9422(81)80140-9
(1981)Doi:10.1002/hlca.19810640824
(1981)Doi:10.1007/BF00900006
(1981)Doi:10.1021/jo01140a017
(1952)Doi:10.1246/cl.1981.1725
(1981)
