SYNTHESIS OF NUCLEOSIDE PHOSPHOTRIESTERS CONTAINING AMIDATE OR THIOATE FUNCTIONS

DOI: 10.1246/cl.1981.1725

Source and publish data:

Chemistry Letters p. 1725 - 1728 (1981)

Update date:2022-09-26

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Authors:

Boeckel, Stan A.A. van

Marel, Gijs van der

Wille, Gerry

Boom, Jacq H. van

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Article abstract of DOI:10.1246/cl.1981.1725

Phosphorylation of properly protected nucleosides with aryl or alkyl phosphorodichloridates, in the presence of 1-hydroxybenztriazole, gives phosphorylated intermediates which react smoothly with different amine or thiol functions to afford the correspond

Full text of DOI:10.1246/cl.1981.1725

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