Tetrahedron p. 2843 - 2854 (1981)
Update date:2022-08-03
Topics:
Stella, L.
Raynier, B.
Surzur, J. M.
The synthesis of a series of 3-aryl 5-hexenyl amines and the cyclisations of the corresponding N-chloroamines are described.When the ring closure results from the amino radical addition to the ethylenic double bond, 2-chloromethyl 4-phenyl piperidines are obtained.These compounds lead by intramolecular Friedel-Crafts reaction to varied substituted 6,7-benzomorphanes.When the phenyl ring is substituted with a methoxyl group, the cyclisation proceeds via homolytic aromatic substitution and 4-allyl tetrahydroquinolines are formed.
View Morewebsite:http://www.aecochemical.com
Contact:+86-592 599 8717
Address:No 611 Sishui Road,Huli
Shanghai Forever Synthesis Co.,Ltd.
Contact:021-61124658
Address:Zhoukang Road,Pudong New District,Shanghai,China
Dongying J&M Chemical Co., Ltd,
Contact:546-8551108
Address:Room 1219, Zisheng Mansion, Zibo Road, Dongying, Shandong, China
Fujian Huitian Biological Pharmacy Co., Ltd.
Contact:0086-598-8300831; 8339920
Address:No.46,Taijiang Road,Sanming City,Fujian,China
Jinan Jianfeng Chemical Co., Ltd
Contact:0086-531-88110457
Address:sales01(-a-t-)pharmachemm{dot}c+o+m
Doi:10.1039/c39930000923
(1993)Doi:10.1021/ja045284s
(2004)Doi:10.1248/cpb.29.3099
(1981)Doi:10.1021/jo00346a051
(1982)Doi:10.1016/S0040-4039(02)01133-4
(2002)Doi:10.1055/s-1982-29775
(1982)
