Journal of Medicinal Chemistry p. 170 - 181 (1986)
Update date:2022-08-03
Topics:
Stokker, G. E.
Alberts, A. W.
Anderson, P. S.
Cragoe, E. J.
Deana, A. A.
et al.
The syntheses of a series of 7-(3,5-disubstituted <1,1'-biphenyl>-2-yl)-3,5-dihydroxy-6-heptenoic acids and their lactones are reported.Intrinsic 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitory activity is enhanced markedly when the biphenyl mo
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