Journal of Organic Chemistry p. 1494 - 1500 (1982)
Update date:2022-09-26
Topics:
Garst, Michael E.
Bonfiglio, John N
Marks, Jeffrey
The hydroboration-carbon monoxide insertion of several bis-olefinic derivatives has provided facile preparations of N-(carbomethoxy)-5-azacyclooctanone (6), N-(carbobenzyloxy)-5-azacyclooctanone (9), and N-(carbobenzyloxy)-5-cyclononanone (18).Of the hydroboration protocols examined, thexylborane-cyanidation proved to be the most useful.Reductive ring closure of 9 and of 18 gave 26 and 27, respectively.Methylation of 9 followed by reduction afforded 29 and 30.
View Morewebsite:http://www.herbpurify.com
Contact:0086-028-85249238
Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China
JiangXi Keyuan Biopharma Co., LTD.
Contact:+86-563-6833666
Address:Guangde Fine Chemical Zone, Anhui Province, China
Tianjin Emulsion Science&Technology Development Co.,Ltd
Contact:13901380442
Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China
website:http://www.hanwayschem.com
Contact:+86-18502787239(whatsapp)
Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD
Contact:86-21-60560171
Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Doi:10.1002/anie.199719891
(1997)Doi:10.1021/ja00362a036
(1983)Doi:10.1134/S1070428011070177
(2011)Doi:10.1021/ol048568q
(2004)Doi:10.1002/jhet.5570180704
(1981)Doi:10.1002/chem.201803143
(2018)