A SIMPLIFIED STRATEGY FOR THE SYNTHESIS OF DIDEOXYRIBONUCLEOTIDE BLOCKS

DOI: 10.1016/S0040-4039(01)81907-9

Source and publish data:

Tetrahedron Letters p. 3367 - 3370 (1981)

Update date:2022-08-04

Topics:

Authors:

Sadana, K. L.

Hruska, F. E.

Loewen, P. C.

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Article abstract of DOI:10.1016/S0040-4039(01)81907-9

The rapid synthesis of dideoxyribonucleotide blocks in 60-85percent isolated yields has been achieved by combining the phosphorylation and condensation steps in a sequential reaction series which also allows the recovery of unreacted nucleotides.

Full text of DOI:10.1016/S0040-4039(01)81907-9

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