Bioorganic and Medicinal Chemistry Letters p. 1353 - 1357 (2006)
Update date:2022-08-05
Topics:
Richardson, Christine M.
Williamson, Douglas S.
Parratt, Martin J.
Borgognoni, Jenifer
Cansfield, Andrew D.
Dokurno, Pawel
Francis, Geraint L.
Howes, Rob
Moore, Jonathan D.
Murray, James B.
Robertson, Alan
Surgenor, Allan E.
Torrance, Christopher J.
Crystallographic and modelling data, in conjunction with a medicinal chemistry template-hopping approach, led to the identification of a series of novel and potent inhibitors of human cyclin-dependent kinase 2 (CDK2), with selectivity over glycogen syntha
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