β-lactams as formal dipoles through amide-bond activation

DOI: 10.1002/ejoc.201501342

Source and publish data:

European Journal of Organic Chemistry p. 549 - 555 (2016)

Update date:2022-08-02

Topics:

Authors:

Barbier, Vincent

Marrot, Jrme

Couty, Franois

David, Olivier R. P.

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Article abstract of DOI:10.1002/ejoc.201501342

Activation of β-lactams can be achieved by simple Lewis-base catalysis to trigger an unprecedented reaction based on the formal dipolar behaviour of a strained amide bond. A new synthetic route for 1,3-oxazinan-6-ones is presented by reaction of β-lactams

Full text of DOI:10.1002/ejoc.201501342

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