Electrochemical Models for Cytochrome P-450. N-Demethylation of Tertiary Amides by Anodic Oxidation

DOI: 10.1021/jo00271a040

Source and publish data:

Journal of Organic Chemistry p. 2446 - 2451 (1989)

Update date:2022-08-05

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Authors:

Hall, Larry R.

Iwamoto, Reynold T.

Hanzlik, Robert P.

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Article abstract of DOI:10.1021/jo00271a040

Anodic oxidation of N,N-dimethylamides in acetonitrile/water (95:5) containing NaClO4 gives the corresponding N-methylamides in high yields.N-Methyl-N-(hydroxymethyl)benzamide was isolated as an intermediate in the electrochemical N-demethylation of N,N-d

Full text of DOI:10.1021/jo00271a040

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