Preparation of the α and β anomers of 9-(3,5-Dideoxy-D-glycero-pent-4-enofuranosyl)adenine and their activity with leukemia L1210 cells in vitro

Article abstract of DOI:10.1021/jm00349a011

A previously reported preparation of 9-(3,5-dideoxy-β-D-glycero-pent-4-enofuranosyl)adenine (5) was not correct. A new synthesis of 5 is described. 3,5-Dideoxy-5-iodo-1,2-O-isopropylidene-α-D-erythro-pentofuanose (1) and 3,5-dideoxy-5-iodo-1,2-O-isopropyl