Double-Head Haptens. Synthesis of and Experimentally Induced Contact Sensitivity to Substances Containing Two Unrelated Haptens, Pyrocatechol and α-Methylene-γ-butyrolactone, in the Same Molecule

Article abstract of DOI:10.1021/jm00348a008

A "double-head" hapten containing a pyrocatechol and an α-methylene-γ-butyrolactone moiety (3) and "monofunctional haptens" with either one of these moietes (18 and 19) connected by a six-carbon chain have been synthesized, and their sensitizing capacity