Journal of the American Chemical Society p. 4666 - 4671 (1982)
Update date:2022-08-04
Topics: Ketones Enzymes Substrates Stereoselective Organic synthesis Heterocyclic Reductions
Haslegrave, J. Anthony
Jones, J. Bryan
Horse liver alcohol dehydrogenase (HLADH) has been found to be an efficient catalyst for the reduction of O-heterocyclic ketones.Preparative-scale HLADH-catalyzed reductions of 2-substituted tetrahydropyran-4-ones are enantioselective, with reduction of e
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(1982)
