Reaction of Substituted 2- and 4-Methylpyrimidines with Aromatic Carboxylic Acid Chlorides

Article abstract of DOI:10.1007/BF00526092

The effect of substituents in methylpyrimidines on the reaction of the methyl groups with aromatic carboxylic acid chlorides in the presence of triethylamine was studied.It is shown that, depending on the character of the substituents, the reaction with the acid chlorides takes place at the methyl groups or at the ring nitrogen atoms.