Chemistry of Heterocyclic Compounds p. 589 - 593 (1982)
Update date:2022-07-29
Topics:
Grishina
Leshcheva
Sergeev
Potapov
Vovk
The methylation of 1-benzyl-Δ9,10-octahydro-4-quinolone with methyl iodide in the presence of lithium diethylamide in tetrahydrofuran is a regioselective electrophilic substitution reaction, and, depending on the reaction conditions, takes place in the 3 or 8 position of the quinolone system. Deuteration under the same conditions takes place only in the 3 position.
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Doi:10.1007/s10895-017-2078-2
(2017)Doi:10.1021/acs.joc.0c01404
(2020)Doi:10.1016/j.cplett.2004.11.132
(2005)Doi:10.1055/s-0029-1218347
(2009)Doi:10.1039/c39820001051
(1982)Doi:10.1016/j.tetlet.2004.10.125
(2005)
