PROTECTION OF IMIDE GROUP OF URACIL MOIETY BY MEANS OF 2,2,2-TRICHLORO-TERT-BUTYLOXYCARBONYL CHLORIDE: A SELECTIVE SYNTHESIS OF 2'-O-METHYLURIDINE

DOI: 10.1246/cl.1982.965

Source and publish data:

Chemistry Letters p. 965 - 968 (1982)

Update date:2022-08-04

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Authors:

Kamimura, Takashi

Masegi, Tsukio

Hata, Tsujiaki

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Article abstract of DOI:10.1246/cl.1982.965

2,2,2-trichloro-tert-butyloxycarbonyl group (TCBOC) was useful protecting group for the protection of imide function of uracil moiety.Starting from N³-TCBOC uridine derivative, 2'-O-methyluridine was selectively synthesized without formation of N³-methyluridine derivatives.

Full text of DOI:10.1246/cl.1982.965

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