Organic Letters p. 501 - 503 (2004)
Update date:2022-08-05
Topics:
Fleming, Fraser F.
Zhang, Zhiyu
Knochel, Paul
(Equation presented) α-Halonitriles react with organometallic reagents in a facile halogen-metal exchange. The halogen-metal exchange is extremely fast with Grignard and alkyllithium reagents, generating metalated nitriles in situ with aldehyde, ketone, a
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