Tetrahedron Letters p. 6505 - 6508 (1990)
Update date:2022-08-04
Topics:
Paquette, Leo A.
Astles, Peter C.
Pseudopterolide is efficiently transformed into tobagolide by reaction with dimethylamine.Sequential treatment of tobagolide with methyl iodide and sodium hydride results in intramolecular SN'displacement with reconstruction of pseudopterolide.
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