Mannich Bases of 4-Phenyl-3-buten-2-one: A New Class of Antiherpes Agent

DOI: 10.1021/jm00357a020

Source and publish data:

Journal of Medicinal Chemistry p. 431 - 436 (1983)

Update date:2022-08-03

Topics:

Authors:

Edwards, M.L.

Ritter, H.W.

Stemerick, D.M.

Stewart, K.T.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00357a020

The morpholine Mannich base of 4-phenyl-3-buten-2-one was found to have activity in model infections of herpes simplex.The activity was essentially equivalent to that of disodium phosphonoacetate.This paper presents the biological activity and synthesis o

Full text of DOI:10.1021/jm00357a020

Products guided by the article

Product name:(E)-α-(2-phenylethenyl)-4-morpholinepropanol hydrochloride

Cas No:84175-32-6

R&D Labs maybe for 84175-32-6

Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
ZK Biochem Group Co., Ltd

Contact:+86-532-80762375

Address:No. 6, Hongkong Middle Road, Qingdao, China
Inner Mongolia Yong Ming Technology Co., Ltd(expird)

Contact:15548878959

Address:Room 1102, Block A, Builing 11, Wanda Plaza
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Shanghai Dianyang Industry Co.,ltd

Contact:+86 21 6492 4669

Address:Chejing RD, Songjiang District, Shanghai, China

Relevant to this article

"&α-METHYLENE-&γ-PHOSTONES" (5,5-DI- AND 5-MONOALKYL-2-METHOXY-3-METHYLENE-1,2-OXAPHOSPHOLAN-2-ONES). A PHOSPHORUS ANALOG OF THE ONE-STEP REFORMATSKY SYNTHESIS OF &α-METHYLENE-&γ-BUTYROLACTONES FROM KETONES AND ALDEHYDES

Doi:10.1016/S0040-4039(00)88668-2
(1982)
Powerful N-monoalkylation of linear tetraamines via bisaminal intermediates

Doi:10.1002/ejoc.200400459
(2004)
Reactions between Dinuclear Metal Carbonyl Complexes and Alkyl Halides: Formal Oxidative Addition across a Metal-Metal Single Bond

Doi:10.1039/c39850001287
(1985)
Generation and Ring Opening of 2,3-Dilithio-1-(phenylsulfonyl)indole

Doi:10.1021/jo00152a041
(1983)
SPELEANDS. Macropolycyclic receptor cages based on binding and shaping sub-units. Synthesis and properties of macrocycle-cyclotriveratrylene combinations

Doi:10.1002/hlca.19820650623
(1982)
Doi:10.1021/jo01074a041
(1960)

Article Doi