Tetrahedron Letters p. 3463 - 3466 (1982)
Update date:2022-08-03
Topics:
Corey, E. J.
Hoover, Dennis J.
The first total synthesis of 5-desoxyleukotriene D (14) is reported.The route of synthesis utilizes a novel method for five-carbon chain extension.The availability of 14 allowed experimental demonstration that the 5-hydroxyl function is important for biological activity of the slow reacting substances.
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(2004)Doi:10.1002/jlcr.3877
(2020)Doi:10.1021/jm058167w
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(2014)Doi:10.1016/S0040-4039(00)85769-X
(1982)
