Chemical and Pharmaceutical Bulletin p. 2255 - 2261 (1992)
Update date:2022-08-04
Topics:
Kitamura
Harano
Hisano
A simple method for synthesis of 2-aryl-substituted 3,3-dimethylindoline derivatives was established by the reaction of 1-acyl-2-hydroxy-3,3-dimethylindoline with electron-rich arenes in the presence of boron trifluoride-diethylether in dioxane. In the reaction with β-naphthol, a pair of isolable diastereomeric atropisomers was isolated. The conformations of both atropisomers were determined by single crystal X-ray analyses. The substitution reaction behavior toward various arenes was accounted for in terms of frontier molecular orbital (FMO) theory.
View MoreDalian RSD International Trade Co.,Ltd.(expird)
Contact:86-22-60875058 58610575
Address:Wantong International Areas, Hongqiao District, Tianjin, China.China
shanghai hekang chemical co.ltd
Contact:021-54173790
Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
shanghai jinshan pharmaceutical Co.,Ltd
Contact:021-57363011，13681638167
Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Jinan Hongfangde Pharmatech Co.,Ltd
Contact:86-531-88870908
Address:F Bldg. West Unit North Area of Univ. Tech. Garden Xinyu Rd. Jinan New & High Tech Industry Development Zone Shandong, China
Wuhan Kemi-Works Chemical Co., Ltd
website:http://www.kemiworks.com
Contact:86-27-85736489
Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
Doi:10.1016/S0040-4039(00)88648-7
(1982)Doi:10.1007/s11176-005-0158-5
(2004)Doi:10.1055/s-1982-29921
(1982)Doi:10.1134/S1070363207120201
(2007)Doi:10.1002/anie.201811946
(2018)Doi:10.1016/j.bmcl.2014.07.086
(2014)
